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May 12, 2024 9 min read
The effects of turmeric depend on various factors – acute effects like digestive support can often be felt after just a few hours, while more profound benefits like reducing chronic inflammation require weeks or months of regular use. Learn why this is the case and how you can optimize the effects of turmeric below.
Table of contents
1. What effects of turmeric are known?
2. How do these effects occur in the body with turmeric?
3. What factors influence how quickly turmeric works?
4. When does turmeric work - guidelines
5. Frequently asked questions about turmeric: when does it work?
6. Conclusion
Turmeric, or Curcuma longa, is a vibrant turmeric root from the ginger family that has been used in Ayurvedic and traditional Chinese medicine for thousands of years. Originally from Southeast Asia, it has a firm place not only in cooking as a spice but also in natural medicine. The active ingredient curcumin is responsible for many of the health benefits of turmeric root and gives the root its characteristic yellow color and effects.
Anti-inflammatory properties
Turmeric is known for its powerful anti-inflammatory effects. Curcumin can reduce chronic inflammation, which is often the basis for diseases such as osteoarthritis, diabetes, or cardiovascular disease. This effect is so potent that some studies have compared it to anti-inflammatory medications—but without the typical side effects.
Antioxidant effect
Free radicals can damage cells and tissue, promoting aging and disease. Turmeric counteracts this process through its antioxidant properties. It neutralizes free radicals while simultaneously stimulating the body's own antioxidant mechanisms.
Supports digestion
Turmeric promotes bile production, which improves fat digestion. It also relieves digestive discomfort such as bloating, fullness, and heartburn. It supports the health of the intestinal flora and has an anti-inflammatory effect on the gastrointestinal tract.
Protection against chronic diseases
Studies show that turmeric can reduce the risk of certain chronic diseases:
Cancer prevention: Curcumin can inhibit the growth of tumor cells and slow their spread.
Heart health: Lowering cholesterol and improving vascular health reduces the risk of heart attacks and strokes.
Neuroprotection: Turmeric can reduce inflammatory processes in the brain and thus prevent neurodegenerative diseases such as Alzheimer's and Parkinson's.
General health promotion
Turmeric supports liver function, strengthens the immune system, and promotes faster recovery from illness or injury. It is also valued as a natural mood enhancer and has been studied in the treatment of depression.
The effects of curcumin are based on biochemical processes that occur in the body at the cellular and molecular level. Curcumin interacts with various signaling pathways, enzymes, and cell receptors to exert its health-promoting effects.
Curcumin inhibits pro-inflammatory signaling pathways, particularly through the regulation of NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells).
Mechanism:
NF-κB is a central regulator of the inflammatory response and promotes the release of cytokines such as tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6) and interleukin-1β (IL-1β).
Curcumin blocks the activation of NF-κB, thereby reducing the production of pro-inflammatory molecules.
It also inhibits the enzymes COX-2 (cyclooxygenase-2) and LOX (lipoxygenase), which are involved in the synthesis of pro-inflammatory prostaglandins and leukotrienes.
Curcumin acts as a direct radical scavenger and at the same time strengthens the body's own antioxidant defenses.
Mechanism:
Curcumin neutralizes free radicals (reactive oxygen and nitrogen species, ROS and RNS) through electron donation.
It activates enzymes such as superoxide dismutase (SOD), catalase and glutathione peroxidase, which are responsible for the degradation of ROS.
Curcumin also promotes the synthesis of glutathione, one of the most important cellular antioxidants.
Curcumin influences signaling pathways that control cell growth and apoptosis, thereby inhibiting the development of cancer cells.
Mechanism:
Curcumin inhibits the activity of mTOR (mammalian target of rapamycin) and Wnt/β-catenin, which are responsible for uncontrolled cell growth.
It promotes the activation of caspases, enzymes that initiate programmed cell death (apoptosis).
By inhibiting angiogenesis (blood vessel formation), curcumin suppresses the supply of oxygen and nutrients to tumors.
It acts on p53, a tumor suppressor protein that detects DNA damage and initiates repair or apoptosis.
Curcumin improves vascular function through endothelial cell regulation and has a cardioprotective effect.
Mechanism:
It increases the availability of nitric oxide (NO), a molecule that dilates blood vessels and lowers blood pressure.
The antioxidant effects reduce oxidized LDL cholesterol, which is involved in the development of arteriosclerosis.
Curcumin reduces the expression of adhesion molecules that are responsible for the attachment of immune cells to the vessel walls.
Curcumin protects the brain by modulating neuroinflammatory processes and promoting neurogenesis.
Mechanism:
It inhibits inflammatory cytokines and microglial activation in the brain that contribute to neurodegenerative diseases such as Alzheimer's.
Curcumin promotes the production of BDNF (Brain-Derived Neurotrophic Factor), a growth factor important for the formation and repair of neurons.
It reduces the formation of beta-amyloid plaques, which play a central role in the pathogenesis of Alzheimer's disease.
Curcumin affects the secretion of digestive enzymes and the balance of intestinal flora.
Mechanism:
It stimulates the production of bile and thereby improves fat digestion.
Curcumin supports the growth of probiotic bacteria such as Lactobacillus and Bifidobacterium while inhibiting pathogenic germs.
It strengthens the intestinal barrier function by promoting tight junction proteins, which regulate intestinal permeability.
Here are the five most important factors that influence how quickly and effectively turmeric works in the body:
Curcumin has a naturally low absorption capacity. Without appropriate measures, only a fraction of the active ingredients is absorbed by the body.
Optimization: Combination with piperine (from black pepper) or fat (e.g. oil), as well as liposomal preparations or special curcumin extracts.
An adequate amount of curcumin is required to achieve a measurable effect. Too little will have no effect, and too much can cause side effects. The daily dose in turmeric supplements usually has a protective rather than a healing effect.
Optimization: Highly concentrated turmeric extracts (e.g. capsules with standardized curcumin content) work faster and more effectively than turmeric powder.
Individual metabolism and age influence how quickly curcumin is processed and broken down. A slower metabolism (e.g., in older people) can prolong the effects.
Optimization: Adapted dosages depending on metabolism and life phase.
Turmeric interacts with other foods and medications, which can affect absorption and effects.
Optimization: Combining with anti-inflammatory substances (e.g., omega-3 fatty acids) can enhance the effect. Caution should be exercised with blood thinners and other medications.
A healthy intestinal flora and an intact intestinal mucosa are crucial for the absorption of curcumin.
Optimization: Supporting gut health with probiotics and a high-fiber diet can enhance the effects of turmeric.
Turmeric, known for its versatile uses and health benefits, is a popular natural treatment option. But how quickly does turmeric actually work? The answer depends on various factors, such as the desired health goal, dosage, method of administration, and the individual body's response.
Turmeric can work quickly in certain cases, especially for acute conditions. These effects often become apparent within hours or days:
Promotes digestion
Turmeric stimulates the production of bile in the liver, which improves fat digestion. Initial improvements are often noticeable within a few hours to days, especially in cases of bloating or fullness.
Anti-inflammatory in the gastrointestinal tract
Curcumin reduces inflammation in the digestive system. Noticeable relief from acute symptoms can occur within a few hours.
Relief of gastrointestinal complaints
Turmeric can reduce symptoms such as cramps, bloating, and fullness. Improvement often occurs within the same day.
For profound health benefits, regular consumption of turmeric over weeks or months is necessary. These effects unfold through its continuous influence on the body:
Antioxidant effect
Protects cells from free radicals and reduces oxidative damage. Initial effects can be noticed after a few weeks, with further buildup over months.
Cancer prevention
Studies suggest that curcumin can inhibit the growth of cancer cells and prevent their spread. These preventative effects require long-term, daily intake over months to years.
Neuroprotection
Supports brain health, reduces inflammation in the brain, and improves cognitive function. Benefits such as a reduced risk of Alzheimer's disease arise from years of continuous use.
Anti-inflammatory treatment for chronic conditions
Relief of chronic inflammation (e.g., in arthritis). Regular intake over 4–8 weeks is required to achieve lasting improvements. Combining it with ginger is beneficial in most cases.
When does turmeric take effect?
The speed at which turmeric works varies depending on the application and individual situation. Here are typical timeframes:
Summary: First noticeable effects
Digestive support: Within a few hours to days
Acute anti-inflammatory therapy: hours to a few days
Chronic inflammation relief: 4–8 weeks
Antioxidant effect: Several days to weeks
Neuroprotection: Months to years
Optimizing the effect
The speed and intensity of the effect can be improved by the correct dosage form and combination:
Increase bioavailability: Combination with piperine (black pepper) or fat improves absorption.
Dosage: Turmeric powder in capsules is a natural and effective way to consume turmeric. For specific needs, higher-dose versions or standardized extracts may provide faster effects.
Regularity: Daily intake is crucial for long-term effects.
Can turmeric be used to treat diseases?
Turmeric is not recommended as a standalone treatment for any disease due to insufficient research and limited bioavailability of curcumin. However, it can be used adjunctive to reduce inflammation or promote overall health.
For what applications is turmeric recommended?
Supports digestion (e.g., in cases of flatulence, feeling of fullness)
Relief of inflammatory conditions (e.g. arthritis)
Promotes antioxidant defense
Prevention of cell damage and support of general health
How quickly does turmeric work?
Turmeric doesn't take effect immediately, but rather unfolds its effects over a longer period of time. Depending on the application, it can take days to weeks for noticeable effects to occur.
For acute complaints (e.g. digestive problems): effect often within a few hours to days.
For inflammation and chronic conditions (e.g. arthritis): Effect usually after a few weeks of regular use.
For general health benefits: Long-term use over several weeks to months can show positive effects.
How quickly does turmeric work against inflammation?
Initial effects can be felt after a few days to weeks of regular use. The effect depends on factors such as dosage, bioavailability (e.g., in combination with piperine from black pepper), and the individual body's response.
How much turmeric should you take per day for inflammation?
For anti-inflammatory effects, a dosage of 500 mg to 2000 mg of curcumin per day is often recommended. Since turmeric powder contains only about 3-5% curcumin, this would equate to 1.5 to 6 g of turmeric powder daily.
Should you always take turmeric with black pepper?
In most cases, this makes sense. Black pepper contains piperine, which increases the bioavailability of curcumin by up to 2000%, thereby enhancing its effects.
When can you take turmeric capsules? Before or after eating?
Turmeric can be taken before or after meals, depending on the desired effect.
Before meals: Can stimulate digestion and support stomach production. Ideal when using turmeric to aid digestion or combat flatulence.
After meals: Promotes curcumin absorption, especially if the meal contains fat. This is recommended if you are taking turmeric for its anti-inflammatory or antioxidant properties.
How can you speed up the effects of turmeric?
Take with fat (e.g. coconut oil, olive oil), as curcumin is fat-soluble.
Use of liposomal curcumin preparations or water-soluble formulations.
Combination with piperine from black pepper.
Regular intake over a longer period of time.
Turmeric doesn't work for me? What should I do?
Check the dosage: Higher concentrations of curcumin may be more effective.
Improve bioavailability: Take turmeric with fat or piperine.
Check quality: Choose high-quality products with standardized curcumin content.
Be patient: Long-term effects often only become apparent after weeks of regular use.
If no effect occurs, consider other natural or medical alternatives.
The time it takes for turmeric to produce noticeable effects depends on the nature of the condition, the method of administration, and individual factors such as metabolism and bioavailability. Acute effects, such as relief from digestive problems, can often occur within a few hours or days. For long-term health benefits, such as reducing chronic inflammation, antioxidant effects, or neuroprotective effects, regular intake over weeks to months is required.
To accelerate the effect, combining it with black pepper (piperine) or fat, as well as using high-quality, bioavailable supplements, is recommended. Patience and consistent use are key to reaping the diverse benefits of turmeric.
Sources:
Razavi BM, Ghasemzadeh Rahbardar M, Hosseinzadeh H. A review of therapeutic potentials of turmeric (Curcuma longa) and its active constituent, curcumin, on inflammatory disorders, pain, and their related patents. Phytother Res. 2021;35(12):6489-6513. doi:10.1002/ptr.7224
Khosravi MA, Seifert R. Clinical trials on curcumin in relation to its bioavailability and effect on malignant diseases: critical analysis. Naunyn Schmiedeberg's Arch Pharmacol. 2024;397(5):3477-3491. doi:10.1007/s00210-023-02825-7
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