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May 02, 2024 11 min read
The golden-yellow spice from the ginger family has gained considerable attention in recent years due to its diverse health benefits. In addition to its ability to treat depression, turmeric also shows potential in managing everyday anxiety and promoting a more balanced mood. One question that arises repeatedly is: Does turmeric boost mood? Turmeric, scientifically known as Curcuma longa, has received particular attention for its health benefits. In this article, I would like to explore the effects of turmeric on the psyche and present recent study results that show that this spice may play an important role in the treatment of depression and anxiety.
The effects of curcumin, the main active ingredient in turmeric, on the brain and psyche
Current clinical studies on the effectiveness of turmeric in depression and anxiety
The challenges of curcumin bioavailability
Possible side effects of turmeric
Practical tips for integrating turmeric into your daily routine to support mental health
Curcumin, the main active ingredient in turmeric and a key component in curcumin, has received considerable research attention in recent years due to its antioxidant and anti-inflammatory properties. Clinical studies suggest that curcumin also plays an important role in regulating neurotransmitters such as serotonin and dopamine in the brain, which are responsible for our mood and emotional stability. The active ingredients in curcumin, especially curcumin, contribute to the regulation of these neurotransmitters, thus supporting emotional stability and mood regulation. A disruption of the balance of these neurotransmitters has been linked to the development of depression and anxiety.
A randomized, double-blind, placebo-controlled study investigated the efficacy of turmeric in patients with major depression . Participants received either a turmeric extract containing 500 mg of curcumin or a placebo for 8 weeks. The results showed that turmeric supplementation led to a significant improvement in depression symptoms, particularly in patients with atypical depression. (Lopresti et Drummond (2017))
Another study compared the effectiveness of curcumin with that of a conventional antidepressant in patients with major depression. Participants received either 500 mg of curcumin, 20 mg of the antidepressant fluoxetine, or a combination of both. After 6 weeks, curcumin was found to be as effective as fluoxetine in treating depression, while the combination of both substances had the strongest effect. (Kanchanatawan et al. (2018))
A 2020 meta-analysis of ten randomized controlled trials with a total of 531 participants found a significant effect of curcumin on depressive symptoms. The authors concluded that curcumin, in addition to standard treatment, could improve depressive and anxiety symptoms in people with depression. (Fusar-Poli et al. (2020))
These study results suggest that turmeric has the potential to alleviate symptoms of depression and support mental health. The exact mechanisms of curcumin's action in the brain are not yet fully understood, but its antioxidant and anti-inflammatory properties are thought to play an important role. Curcumin may help reduce oxidative stress and chronic inflammation in the brain, which are linked to the development of mental health disorders.
Some studies also suggest that curcumin may increase levels of brain-derived neurotrophic factor (BDNF), a protein important for nerve cell growth and function that is often reduced in depressed patients. (Hurley et al. (2013))
One challenge with using turmeric as a dietary supplement is the low bioavailability of curcumin. This means that only a small portion of the curcumin consumed can actually be absorbed and utilized by the body.
One possibility is to combine the effects of turmeric with piperine, a component of black pepper. Piperine can increase the bioavailability of curcumin by up to 2000% by inhibiting curcumin degradation in the liver and improving intestinal absorption. Another option is micellar formulations, in which curcumin is encapsulated in fat droplets to facilitate absorption in the body.
By optimizing bioavailability, it can be ensured that the body can reap the full benefits of curcumin without having to ingest large amounts of turmeric.
Turmeric is generally considered safe and well-tolerated, but side effects can occur in rare cases. These include gastrointestinal disturbances such as diarrhea, bloating, or heartburn, especially at higher doses. People with gallstone disease or liver problems should consult their doctor before taking turmeric supplements, as curcumin can stimulate bile production.
There are preparations that minimize the risk of side effects by ensuring precise dosages and pure ingredients. These products are said to have strict quality controls and contain no additives or fillers that could cause further side effects. Optimal composition can improve bioavailability and achieve a better effect-to-side effect ratio even at lower dosages.
It's important to emphasize that turmeric is not a substitute for professional medical treatment for mental health conditions. If symptoms of depression or anxiety persist or become severe, a doctor or mental health professional should always be consulted. However, turmeric can be considered as a complementary measure to support mental health.
Curcumin, the main active ingredient in turmeric, is a versatile molecule with a wide range of health benefits. In addition to its mental health benefits, curcumin has also demonstrated anti-inflammatory, antioxidant, and anti-cancer properties. It has been used in traditional Indian and Chinese medicine for centuries to treat various conditions. Turmeric extract, particularly curcumin, has shown potential antidepressant properties in studies and may have a positive effect on mental health through its anti-inflammatory effects, particularly in relieving symptoms of depression.
Studies have shown that curcumin may also play an important role in the prevention and treatment of Alzheimer's disease, arthritis, diabetes, and cardiovascular disease. Curcumin's anti-inflammatory properties may help reduce chronic inflammation in the body, which is implicated in the development of many diseases.
Curcumin also has powerful antioxidant properties and can help neutralize free radicals in the body. Free radicals are unstable molecules that can cause cell damage and contribute to the development of chronic diseases and premature aging. By neutralizing free radicals, curcumin can help protect the body from oxidative stress.
In order to make the most of the effects of turmeric on the psyche, a sufficient dosage of the active ingredient curcumin is crucial.
The recommended dosage of turmeric to support mental health is 500-1000 mg of curcumin per day, divided into two or three doses. For depression and anxiety, higher doses of up to 1500 milligrams of curcumin per day can be considered, but this should always be done in consultation with a doctor or therapist.
It's important to note that the effects of turmeric on mental health aren't immediate, but develop over time. In most studies, participants were treated with turmeric for a period of 4 to 8 weeks before a significant improvement in symptoms was observed. It's therefore important to be patient and continue taking turmeric for a sufficient period of time to reap the full benefits.
Turmeric dosage plays a crucial role in its effectiveness in supporting mental health. As mentioned above, the recommended dosage for the prevention and treatment of depression and anxiety is 500–1500 milligrams of curcumin per day. However, it's important to note that the optimal dosage can vary from person to person and depends on factors such as age, weight, metabolism, and the severity of symptoms.
Studies have shown that higher doses of curcumin tend to have a stronger effect on mental health than lower doses. A meta-analysis by Ng et al. (2017) examined the results of six randomized controlled trials on the efficacy of curcumin in depression. The analysis showed that doses of 1000 mg of curcumin per day or higher led to a significant improvement in depression symptoms, while lower doses had no significant effects.
However, it's important to emphasize that higher dosages may also be associated with an increased risk of side effects. Dosages above 2000 mg of curcumin per day, in particular, may increase gastrointestinal symptoms such as diarrhea, flatulence, or heartburn. It is therefore advisable to increase the dosage slowly and pay attention to individual tolerance.
Turmeric can not only support existing mental health conditions such as depression and anxiety, but can also be used preventively to reduce the risk of developing these conditions. Curcumin's anti-inflammatory and antioxidant properties can help maintain the balance of neurotransmitters in the brain and protect against stress-related damage.
One study investigated the effects of curcumin on stress resistance and cognitive performance in healthy adults. Participants received either a placebo or a turmeric extract containing 400 mg of curcumin per day for a period of four weeks. The results showed that taking curcumin led to a significant improvement in stress resistance and cognitive performance, particularly in tasks requiring attention and working memory. (Lopresti et al. (2015))
These results suggest that turmeric can also be used in healthy individuals to strengthen mental resilience and improve well-being. Especially during times of high stress, regular consumption of turmeric may help reduce susceptibility to stress-related mental health conditions such as depression and anxiety.
However, it's important to emphasize that turmeric is not a substitute for a healthy lifestyle and a balanced diet. A combination of regular exercise, adequate sleep, stress management, and a nutrient-rich diet forms the foundation for good mental health. Turmeric can be used as a complementary measure to further enhance the positive effects.
Turmeric is not only available as a dietary supplement but can also be naturally consumed through the diet. Turmeric is a staple ingredient in Indian, Pakistani, and Thai cuisine, lending its characteristic yellow color to curries, soups, and rice.
Turmeric is also increasingly being used in Western cuisine, not only for its unique flavor but also for its health benefits. Turmeric can be incorporated into smoothies, teas, dressings, or spreads, adding an exotic touch to dishes.
A particularly popular preparation is the so-called "golden milk," also known as a turmeric latte. Turmeric is boiled in milk or plant-based milk along with other spices such as cinnamon, ginger, and black pepper, often sweetened with a little honey or agave syrup. This beverage not only tastes delicious but can also help improve the bioavailability of curcumin and enhance its anti-inflammatory effects.
Those who want to incorporate turmeric into their diet can start with small amounts and gradually increase the dosage according to taste and tolerance. A daily dose of 1 to 2 teaspoons of turmeric powder is considered safe and can already have positive health effects.
Chronic inflammation in the body is considered a major cause of many diseases, including depression, cardiovascular disease, diabetes, and cancer. Due to its powerful anti-inflammatory properties, turmeric has the potential to counteract these inflammatory processes and reduce the risk of inflammation-related diseases.
The anti-inflammatory effect of turmeric is primarily due to its active ingredient curcumin. Curcumin can inhibit the production of pro-inflammatory cytokines such as TNF-alpha and interleukin-6 while simultaneously promoting the production of anti-inflammatory cytokines such as interleukin-10. Thus, curcumin can help restore the balance between pro- and anti-inflammatory processes in the body.
Studies have shown that curcumin can have positive effects on various inflammation-related diseases such as rheumatoid arthritis, inflammatory bowel disease, and psoriasis. Curcumin can also be beneficial in treating depression and anxiety, which are often associated with chronic inflammation in the body.
To maximize the anti-inflammatory effects of turmeric, regular intake over a long period of time is recommended. As mentioned above, turmeric can be consumed both through diet and in the form of supplements. A combination of both approaches can help maximize the positive effects of turmeric on inflammatory processes in the body.
Turmeric can be incorporated into your daily routine in a variety of ways to support mental health and improve overall well-being. Here are some practical approaches:
Turmeric tea:
Make a tea with fresh turmeric, ginger, lemon, and honey. This tea not only tastes delicious, but can also help detoxify the body and stimulate digestion.
Golden milk:
Boil turmeric powder with other spices like cinnamon, cardamom, and black pepper in milk or plant-based milk. Sweeten with honey or agave syrup if desired. This drink is especially good in the evening, as it can have a relaxing and sleep-inducing effect.
Anti-inflammatory smoothies:
Add a teaspoon of turmeric powder to your smoothies. Turmeric's anti-inflammatory and antioxidant properties can help protect the body from free radicals and support post-exercise recovery.
Curries and spreads:
Use turmeric as a spice in curries, soups, or spreads. Combining it with black pepper can help improve the bioavailability of curcumin.
Dietary supplement as capsule, pay attention to the dosage:
If you want to ensure you're getting adequate amounts of curcumin, capsule supplements can be a good option. Look for high-quality products with a standardized curcumin content.
It's important to note that turmeric's psychological effects vary from person to person. While some people notice an improvement in mood and a reduction in anxiety after a short period of use, others may take longer to experience noticeable effects. Be patient and give turmeric some time to take full effect.
Turmeric is a versatile spice with an impressive range of health benefits. Research in recent years has shown that turmeric may play a particularly important role in the treatment of depression and anxiety. The anti-inflammatory and antioxidant properties of curcumin, the main active ingredient in turmeric, may help maintain the balance of neurotransmitters in the brain and protect against stress-related damage. (Kaufmann et al. (2016))
Taking turmeric in supplement form or incorporating it into your daily diet can be a valuable complementary measure to support mental health. However, it's important to emphasize that turmeric is not a substitute for professional medical treatment for mental health conditions. If symptoms persist or become severe, you should always consult a doctor or therapist.
There's no one-size-fits-all answer to the question of what the best natural antidepressant is. Every person is unique and responds differently to different treatment approaches. In addition to turmeric, there are other natural substances such as St. John's wort, omega-3 fatty acids, or saffron that can be helpful for depression and anxiety. Ultimately, it's important to find the right approach for each individual and implement it in consultation with a doctor or therapist.
In the future, research into turmeric and its constituents will surely yield many exciting discoveries. We are convinced that this versatile spice will continue to play an important role in natural medicine and disease prevention for years to come. Turmeric root, known for its traditional use in cooking and medicine, offers significant health benefits, including its anti-inflammatory and antioxidant effects.
Sources:
Fusar-Poli L, Vozza L, Gabbiadini A, et al. Curcumin for depression: a meta-analysis. Crit Rev Food Sci Nutr . 2020;60(15):2643-2653. doi:10.1080/10408398.2019.1653260
Lopresti AL, Drummond PD. Efficacy of curcumin, and a saffron/curcumin combination for the treatment of major depression: A randomized, double-blind, placebo-controlled study. J Affect Disorder. 2017;207:188-196. doi:10.1016/j.jad.2016.09.047
Kanchanatawan B, Tangwongchai S, Sughondhabhirom A, et al. Add-on treatment with curcumin has antidepressant effects in Thai patients with major depression: A randomized double-blind placebo-controlled study . Neurotox Res. 2018;33(3):621-633. doi:10.1007/s12640-017-9827-8
Ng QX, Koh SSH, Chan HW, Ho CYX. Clinical use of curcumin in depression: A meta-analysis . J Am Med Dir Assoc. 2017;18(6):503-508. doi:10.1016/j.jamda.2016.12.071
Lopresti AL, Maes M, Maker GL, Hood SD, Drummond PD. Curcumin for the treatment of major depression: A randomized, double-blind, placebo-controlled study. J Affect Disorder. 2014;167:368-375. doi:10.1016/j.jad.2014.06.001
Kaufmann FN, Gazal M, Bastos CR, Kaster MP, Ghisleni G. Curcumin in depressive disorders: An overview of potential mechanisms, preclinical and clinical findings. Eur J Pharmacol. 2016;784:192-198. doi:10.1016/j.ejphar.2016.05.050
Hurley LL, Akinfiresoye L, Nwulia E, Kamiya A, Kulkarni AA, Tizabi Y. Antidepressant-like effects of curcumin in WKY rat model of depression is associated with an increase in hippocampal BDNF . Behav Brain Res. 2013;239:27-30. doi:10.1016/j.bbr.2012.10.049
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